Bacterial plant diseases caused heavy yield and growth losses to agriculture crops worldwide. Among the most important bacterial plant diseases are soft rot, Pectobacterium carotovorum and crown gall bacteria, Agrobacterium tumefaciens. The application of chemicals to control both diseases affecting environment and consumers health. The antibacterial activity of three methanolic plant extracts , Lantana camara , Rhazya stricta, Ruta chalepensis and and Propolis as a nutral honey product on A. tumenfaciens and P. carotovorum were evaluated. The present study aims to use alternative methods to control these diseases with Propolis as a natural honey product and some plant extracts grown in Saudi Arabia. The propolis extract demonstrated strong inhibition activity against the tested plant pathogenic bacteria. The results showed that the inhibition zones were 14 mm and 13 mm at a concentration of 400 µg/ml for P. carotovorum and A. tumefaciens respectively. The results of L. camara, Rh. stricta and R. chalepensis at the same concentration were 13, 12 and 11 mm for P. carotovorum respectively, where the inhibition zones were 12, 11 and 11mm respectively for A. tumefaciens. The obtained results revealed that Propolis and these plant extracts are new promising potential sources of antibacterial compounds and good future practical applications for plant health. a promised alternatives to control bacterial diseases in field crops to avoid the use of chemical pesticides with harmful effects to environment and human health.