Experiments were conducted in cotton fields in the village of Bahr El-Baker, Sharkia Governorate during 2011 and 2012 cotton seasons to study the effect of Indoxacarb 105ml, Methomyl 300g  and Spinosad  at rates 50,75 and 100 ml/feddan"} on the pink and spiny bollworms. Results showed that Methomyl caused the highest reduction percentage on the pink bollworm 70.24%, followed by Spinosad  100,75 and 50ml with 57.01, 47.56 and 41.36%, respectively, during the two seasons. The least reduction percentage was 31.69% in Indoxacarb. The results, also indicated that Spinosad  at rate 100 ml/ feddan caused the highest reduction percentage in the spiny bollworm where it was 69.50%, followed by Spinosad  75ml then Methomyl and Spinosad  50 ml where it was 58.99, 51.03 and 50.91%, respectively. Indoxacarb recorded the lowest reduction percentage 30.96%. Methomyl caused highest reduction percentage for the pink and spiny bollworms where it was 66.04%, followed by Spinosad  100,75 and 50 ml which  recorded 61.95, 50.90 and 44.65%, respectively. Indoxacarb recorded the lowest reduction percentage 25.61%.