This work was conducted in the AgriculturalExperimentationCenter, Faculty of Agricultural, Al-AzharUniversity, Assiut Branch, during two successive seasons 2007 and 2008. Fifty three genotypes of sweet sorghum(Sorghum bicolor.L) were screened to find out how much each of the resistance variables affects the genotypes resistance against corn and sugar cane borers namely, (Sesamia cretica. Ledder and Chilo agamemnon.Bleszyncki.). The tested trits were plant height, leaves number and number of days to 50 % flowering, T.S.S. %, sucrose % and purity %. Data obtained indicated that the tested genotypes could be divided into four groups according to their susceptibility to borer infestation. The grouping pattern was as follows: (1) highly resistant group (HR) which contained twelve genotypes; (2) moderately resistant  group (MR) which contained thirteen genotypes; (3) low resistant (LR) group which contained twenty genotypes and (4) highly susceptible group (HS) which contained eight genotypes. Highest plant were the genotypes 14R3A, Brandes, 14R1, Wily, 187 and 191 these genotypes significantly surpassed the other genotypes. The earliest flowering was recorded in the follows: genotypes 202, 43, 185, 202R3, 204, 25, Wiley and 80, where the earliest of them was 202. The highest numbers of leaves per plant were recorded to the genotypes 174 and 7R3 followed by 197, 185, 186, 220, 14R3A, 142R3, 43, 134, 222, 203R3, 209 and 39R1. While, the lowest numbers of leaves per plant were obtained from the genotypes 25, 202R3 and 202. The genotype 39R1 recorded the highest percentage of T.S.S. %, while the genotype 44 recorded the lowest percent. The highest percentage of recorded sucrose was
18.2 % in genotype 199 followed by 17.9 %, 17.8 %, 17.6 %, 17.2 % and 17.1 % in genotypes 96, 109, 14R3A, 33 and 195R3, respectively, while the lowest percentage was obtained in the genotypes 44 and Wiley. The genotype 170R1 recorded the lowest percentage of purity and Wiley. On the other hand, the genotypes 33, 70, 199, 96, 187 and 39R3A recorded significantly higher percentage of purity in comparative to the other genotypes. Generally, it could be concluded that the best promising genotypes lines were 195R2A, 203R3, 220, 25, 203, 74, 73, 199, 96 and 109, respectively. These lines had a high T.S.S % and sucrose %. Immunity and resistance against corn and sugar cane borers; they could be propagated to become a good varieties in Middle and Upper Egypt.