This work was conducted on honeybee colonies situated in the apiary of the experimental farm of Fac. Agric. South Valley Univ at Qena in the period from 3 Oct. till 28 Nov. 2009.to evaluate the effect of some honey bee products as well as   two plant materials for controlling Varroa mite on adult worker bees and in sealed worker brood .The used materials were honey solution, bee venom solution, royal jelly solution, honey bee larval extract, El-ader(Artemisia  monosperma)  leaves extract, and worm wood (Herba alba asso.) extract. It was found that the reduction percentages in Varroa mite on adult bees were: 79.38, 74.15, 73.75, 66.54 57.67 and 49.13%, while the reduction percentages in Varroa mite in sealed worker brood were: 90.07, 89.83, 84.61, 74.08, 76.31 and 72.37% for the previous materials, resp. For control colonies, the percentage of infestation was increased from 36.00 to 48.25% on adult bees  and from 22.40 to 28.20%  in sealed worker brood.