Results indicated variation effects of certain bio-control compounds (Spinosad and Agrin), plant extract (Tagetes), IGR (Consult) and Cypermethrin & its mixtures [(Spinosad+Tagetes (3:1), Spinosad+Tagetes (1:3)] and Cypermethrin+ Agrin (3:1) in comparison with Trichogramma evanescens parasitoids on some biological parameters   of Pectinophora gossypiella and Earias insulana such as%hatching, %larval  mortality, larval and pupal weight, %pupation and adult emergence, larval and pupal duration, pupal and adult deformations, as well as effects on yield and yield loss after infestationunder laboratory and field conditions on cotton plants in Minia Governorates.