Two sprays of cyanophos were applied on cotton plants adjacent to maize field by two methods of application, i.e. micron ULVA and a motorized knapsack mistblower. Operator exposure during application, drift residues on maize plants and the toxicity of these residues on fish and honeybees were estimated. Fish and bees were located on the ground of maize field at different distances from the edge of the cotton field. Dermal exposure was determined by measuring cyanophos on pieces of clothing fitted to applicator overall within the time specified for application. Results show that the higher level of deposition of the insecticide on the total area of all cloth patches fitted on different body regions was observed for the micron ULVA (total deposition for the two sprays was 11.8 mg within exposure time of 9.5 min versus 3.82 mg for the mistblower at the same exposure time). Deposition on different body organs could be arranged descendingly as follows: hands> legs> knees> chest> elbows or shoulders. Deposition was more in 1^st spray than in 2^nd one, mainly due to the difference of wind speed. At the 1^st spray, distances traveled by cyanophos residues were 24 and 33 m when using the mistblower and micron ULVA, respectively. At these distances, the corresponding values of mean deposits were 16.5, 11.6 µg/kg of maize leaves, respectively. At 2^nd spray (lower wind velocity) the distances were 18 and 24 m corresponding to 19.3 and 10.6 µg/kg maize leaves, respectively. Drift of cyanophos released by each of the tested equipment caused 100% mortality of fish and honeybees placed at the distances 3 and 6 m, respectively. Zero mortality for both organisms were observed at distances 18 and 30 m for the mistblower and micron ULVA, respectively. It is obvious that levels of dermal exposure or drift to non-target sites were higher for micron ULVA than for the mistblower. These levels were markedly affected by wind speed.