Thirteen cultivars of cucumber Cucumis sativus and eight cultivars of watermelon Citrullis  vulgaris were evaluated for their host response to Meloidogyne javanica. The nematode succeeded in developing and multiplying on all most tested cultivars from Cucurbitaceae plants. Cucumber cultivars Hisham, Waffir and Beitalpha the highest rate of nematode reproduction more than the rest of cultivars  Emparator, Hayel and Sinai1 were classified as  slightly resistant (SR ). While  cultivars cucumber Bahy, BashaF1,Beitalpha, Ellama, Eshrak1, Fahd, HadyF1, Hisham,Paracoda, Waffir were classified as susceptible (S) hosts to M.javanica.  Also, results showed that some of tested watermelon cvs  Aswan F1, Giza 1, Giza 21 and Sugar Baby  were classified as slightly resistant (SR) , and four cvs  Al-Fahd, Al-Gawhra ,Charleston Gray123 and Crimson Sweet were classified as susceptible(S) hosts. Moreover, there were significant reduction in both shoot and root fresh weights of the tested all cultivars infected.