The bed bug, Cimex lectularius L., is a hard pest to control. The occurrence of insecticidal resistance amongst bed bug populations and concerns over human-insecticidal exposure has motivated the development of alternative bed bug control measurements. Therefore, the present study aimed to evaluate the efficacy of five essential oil products (Cinnamon oil, Clove oil, Garlic oil, Peppermint oil, and Thyme oil) compared to two pyrethroid products (Deltamethrin and Cypermethrin), and one organophosphorus (Diazinon) against field strain of bed bug (Cimex lectularius L.). The obtained results indicated that among the five essential oils, the Clove oil, and Cinnamon oil showed high efficacy against bed bug. Likewise, Deltamethrin exhibited the highest effectiveness among the three insecticides within 90 min after treatment. Also, Diazinon gave the maximum mortality against bed bug amongst the three insecticides tested after 24 hours of treatment. Accordingly, the present study suggested that using natural essential oils could be effective method, somewhat easier, safe and less expensive for controlling bed bugs.