This experiment was carried out at El-Riad region, Kafr El-Sheikh Governorate during two sugar beet successive seasons, 2013 and 2014. The aim of this study examined the efficiency of silica nanoparticles, bioinsecticides (Dipel 2X and Biofly), peppermint extract and insecticide (Match 50% EC) in controlling the cotton leafworm, Spodoptera littoralis (Boisd.) and their effects on some associated natural enemies in sugar beet. Results showed that the chemical insecticide (marshal) was the highest efficiency in controlling the cotton leafworm flowed by silica nanoparticles in high rate. Data showed also the extract of peppermint attractive the natural enemies to sugar beet filed and made moderate control the cotton leafworm.