Trials were conducted in Nubaria district, Behaira Governorate, to evaluate the infestation reduction for the cerambycid borer Niphona picticornis, Muls. infesting grape trees during two successive years 2013 and 2014, dormant pruning alone resulted in 43.22% reduction of infestation during 2013 and increased to 54.04% in 2014, summer pruning resulted in 1.87% and 10% reduction during 2013 and 2014 respectively, while both dormant and pruning summer achieved 46.11% and 58.62% reduction of infestation during the two years of study, respectively. Mechanical treatment recorded 6.68% and 18.26% reduction, while, bioformulations treatments (bacteria and fungi formulations) achieved 3.32% , 6.20% and increased to 7.25%, 10.92% in the two years of study respectively, on the other hand both local painting and local spray treatments using Basudin 60% EC and Cidial 50% EC,  resulted in 47.07% ,42.74%  in 2013 and increased to 56.79%  , 61.41%  reduction of the borer infestation in 2014, finally, the combined treatments i.e., pruning, worming, local painting or local spraying achieved the highest reduction of the borer infestation, reached 81.56 and 79.72% respectively.