The present investigation aims to determine the susceptibility of six  cotton varieties to piercing sucking insects infestation and relative between yield and yield components with   infestation of sucking insect. Six genotypes of cotton were used in this study which namely; Giza 86 (G.86), Giza 88 (G.88), Giza 92 (G.92), Giza93 (G.93), G. 86*10229 and G.84*(G.70*G.51b)* S62 .The results cleared that genotypes mean squares were highly significant for yield and yield components in the two seasons(2012/2013) and combined analysis .Also, genotypes by environments interaction was highly significant for all traits. Also, the means of genotypes were statically different, where the genotypes of 10229 x G.86, G. 92 and Giza 86 recorded the highest values of mean for seed cotton yield and lint percentage and lint index in the first season comparing to their remaining genotypes while, in the second year (2013) the varieties 10229 x G.86, G.92 and (G84*(G70*G.51b)*S₆₂) recorded the highest values of seed cotton yield while, for lint percentage the varieties 10229 x G.86 and G.86 G.93 recorded the highest in this trait. Infestation of piercing-sucking insect, the results cleared that genotypes mean squares were highly significant for Aphis gossypii(Golever) ,Empoasca lybica Beg. and  Bemisia tabaci (Genn) i, except for Nezara viridula L in the two seasons(2012/2013) and combined analysis .Same trend found in genotypes by environments interaction which was highly significant. Also the Egyptian cotton varieties proved to be susceptible to infestation with the sucking insects significant of genotypes  except for N. viridula  which that varieties were more tolerance. The results cleared that Giza 88 was the lowest population density for the A. gossypii and B. tabaci ,while the highest number of the two insect existed on variety Giza 86 x10229 Giza93 and ) (G84*(G70*G.51b)*S₆₂)  ) Although, the new promising hybrid gave high yield.