The efficacy of Agrein, Bioarc, Bionema, Biozeid, Micronema and two entomopathogenic nematodes (EPNs),  Steinernema carpocapsae (All), Heterorhabditis bacteriophora (B20) as biological control agents of Meloidogyne incognita and Rotylenchulus reniformis nematodes infecting papaya, Carica papaya L. were evaluated under greenhouse conditions. All the tested bionematicide and (EPNs) significantly reduced in the numbers of nematodes in soil, galls formation, eggmasses and eggs per eggmass than those in the untreated (check) and improved plant growthparameters. The highly significant increase in weights of both shoot and root of plant grown in soil treated with Agrein and Steinernema carpocapsae. This research may contribute in the novel direction of using bionematicide and entomopathogenic nematodes (EPNs) a biological agent against plant parasitic nematode.