World wide storage of grains is a vitality measure for facing the catastrophes and crises. Through storage the grains are susceptible to infest by many of primary and secondary stored product insects. Heavily application of synthetic chemical insecticides led to environmental  pollution, resistance development and contribution in destroying human health. The present study was conducted to evaluate three biomaterial groups,  plant oils, castor (Ricinus communis) , garlic (Allium sativum)and sesame oil (Sesamum idicum), plant powder, rice hull, maize and cotton stems as well as insect growth regulators, agron (flufenoxuron), alsystin (triflumuron) and match (lufenuron) using two methods of application, common mixing technique and modified mixing of feeding medium ( layer method) against  Sitophilus oryzae (Linnaeus) and Triboluim castanium (Herbst) adults.  The residual activity of  the tested materials also was studied. Based on LC₅₀, IGRs had  the strongest effect followed by plant oils and plant powders. For IGRs alsystin was the premier while garlic oil and rice hull achieved the best activity for plant oils and plant powders, respectively. Results also showed that the three tested groups caused obviously inhibition on progeny with the all tested concentrations, especially at concentration of 10 and 15 ml/kg for plant oils, 10 and 15 g/kg for plant powders and 10 and 15 mg/kg for insect growth regulators that completely prevented any emergence  of adults with both insects, Sitophilus oryzae and Triboluim castanium. Moreover, results cleared that the modified manner (layer technique) protected wheat grain for five months posttreatment. In addition, the down position was the most effective on the tested parameters. In the long run the present study suggests the application layer manner technique which minimizes the direct contamination of grains and rationalized the use of chemical insecticides in stored product insect control. Furthermore the oils or powders may replace the IGRs as alternatives