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50557

Efficiency of Some Anticoagulants Against The Albino Norway Rat, Rattus Norvegicus Under Laboratory Conditions

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Last updated: 22 Jan 2023

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Abstract

This work aim to clear the effect of LD50 values of varied anticoagulants on the body weight reduction, day to death and appetency percentage for male, female and juvenile of the albino Norway rat, R. norvegicus under laboratory conditions. The gained results could be concluded as next: The LD50 values of the treated male, female and juvenile of R. norvegicus with each of Bromadiolone, Difenacoum and Chlorophacinone were; (0.81, 0.91 and 0.78 mg/kg b.w.), (1.40, 1.54 and 1.27 mg/kg b.w.) and (6.02, 6.13 and 5.92 mg/kg b.w.), respectively. These figures proved that adult male was more susceptible than female for the whole tested anticoagulants, meanwhile juvenile was more susceptible than adult. The body weight reduction percentages for male, female and juvenile were; (13.9, 10.7 and 14.3%), (21.8, 13.7 and 13.5%) and (10.2, 10.9 and 18.2%) for Bromadiolone, Difenacoum and Chlorophacinone, respectively. In addition, mean day to death of the treated individuals with LD50 values of Bromadiolone, Difenacoum and Chlorophacinone were (6.0, 6.0 and 4.6 days), (4.0, 6.0 and 4 day) and (6.8, 6.6 and 4.5 day) respectively. In other words, Difenacoum was the most effective one against the experimental individuals followed by Bromadiolone and Chlorophacinone. Also, the results proved that the adult (male and female) and juvenile which treated with the tested anticoagulants lost their appetite for the introduced plain food after the treatment gradually. As well as, the data cleared that there is a positive link between appetency percentage and the body weight reduction for adult (male and female) and juvenile both of R. norvegicus

DOI

10.21608/jppp.2016.50557

Authors

First Name

A.

Last Name

Asran

MiddleName

A.

Affiliation

Plant Protection Research Institute - Agricultural Research Center, Dokki, Giza, Egypt

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Orcid

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First Name

Fatma

Last Name

Khidr

MiddleName

K.

Affiliation

Plant Protection Research Institute - Agricultural Research Center, Dokki, Giza, Egypt

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City

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Orcid

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First Name

Mona

Last Name

Ali

MiddleName

A.

Affiliation

Plant Protection Research Institute - Agricultural Research Center, Dokki, Giza, Egypt

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Orcid

-

First Name

Nadia

Last Name

El-Hawashy

MiddleName

M. S.

Affiliation

Plant Protection Research Institute - Agricultural Research Center, Dokki, Giza, Egypt

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Volume

7

Article Issue

5

Related Issue

7821

Issue Date

2016-05-01

Receive Date

2019-09-30

Publish Date

2016-05-01

Page Start

311

Page End

314

Print ISSN

2090-3677

Online ISSN

2090-3758

Link

https://jppp.journals.ekb.eg/article_50557.html

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https://jppp.journals.ekb.eg/service?article_code=50557

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8

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Original Article

Type Code

888

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Journal

Publication Title

Journal of Plant Protection and Pathology

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https://jppp.journals.ekb.eg/

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Article

Created At

22 Jan 2023