This study was carried out to evaluate the effectiveness of certain bio control agents such as entomopathogenic nematodes (EPNS)(Heterorhabditis bacteriophora (HP88), Heterorhabditis bacteriophora(B20), Steinernema carpocapsae and Steinernema sp.), Bioarc (Bacillus megaterium) and Biozeid (Trichoderma album) against the two land snails, Eobania vermiculata andSuccinea putris compared with recommended molluscicide Agrinate under laboratory conditions. Results revealed that Agrinate showed superior toxicity effect more than tested biological agents recording the highest total mortality percentages in E. vermiculata (86.65%) and S. putris (96.65%). Bioarc and Biozeid ranked the next and induced total mortality percentages amounted to 56.66 and 39.98% for E. vermiculata and 69.98 and 56.66% for S. putris, respectively. Among entomogenous nematodes, H. bacteriophora HP88 and B20 performed the best at the level of 9000 IJs/ cup, while S. carpocapsae and Steinernema sp. showed the least molluscicidal activity against E. vermiculata and S. putris after 28 days of treatment. The land snail, S. putrisshowed more sensitivity to all tested treatments than E. vermiculata.