Field studies were carried out at the experimental farm of Sakhaa, Agricultural Research Station, Kafr El-Sheikh  Governorate during 2014/2015 and 2015/2016 faba bean seasons. Results showed that population of liriomyza trifolii larvae had 3-4 peaks  on faba bean varieties in the frist season ,and 2-3 peak  in the second season. peaks occurred in January, February and March in both seasons, with  the highest one in March  . In the frist season, the highest average number of L. trifolii larvae was recorded on Giza 3 variety with 58.00 larvae /30 leaflets, while the lowest one was on  Misr1 variety, with an average of  45.22 larvae /30 leaflets . In the second season, an opposite the highest average number of the larvae was recorded on Misr1 variety with an average of 49.35 larvae/30 leaflets, while the lowest average number on Sakha 4 with an average 30.52 larvae /30 leaflets. Statistical analysis revealed nonsignificant and significant differences among the 6 tested varieties to infestation with L. trifolii larvae in the first and second seasons, respectively. Concerning leafhoppers, Empoasca spp.  population, there were  2-3 peaks on different faba bean varieties during December, January, February or March in both seasons. The highest peak was recorded in March in both seasons . The highest average number of Empoasca spp. (nymphs and adults ) was recorded on Giza 40 variety with an average of 58.55 indiv. /30 leaflets . the lowest average number of Empoasca spp.was recorded on Sakhaa 3 variety with an average of  42.88 indiv ./30 leaflets in the first season. the opposite occurred  in the second season ,Sakha3 showed the highest average number of jassids with an average of  35.83 indiv. /30 leaflets . the lowest one was Sakha2 variety with an average of  29.38 indiv. /30 leaflets . Statistical analysis showed significant and nonsignificant differences among the 6 tested varieties to infestation with Empoasca spp. in the first and second seasons, respectively. Sakha4 variety showed the highest content of total carbohydrates (52.01%), Silica (2.7%) and chlorophyll (42.2 ppm) and lowest content of protein (16.7%) and lipids (0.93%) which had the lowest average of two seasons for L. trifolii larvae. Giza3 showed the highest content of protein (20%) and silica (2.7%) and lowest content of carbohydrates(46.8%) and chlorophyll (36pmm). Sakha2 contain the highest content of lipids (2.04%) and lowest content of silica (1.4%) and phenol (0.473%) , which had the lowest average of two seasons for Liriomyza trifolii and Empoasca spp. (43larvae and 36.6 indiv./30leaflets, respectively ). Giza40 showed the highest content of phenol (0.583%) which had the highest average number of two seasons for L. trifolii larvae (50.5larvae/ 30 leaflets ) . Results showed that L. trifolii larvae number correlated insignificantly negative with carbohydrates and chlorophyll in both seasons, in addition to protein and silica in the second season. Positive insignificant correlation with lipids and phenol in both seasons .Empoasca spp .population correlated positive insignificant with carbohydrates, silica, phenol and chlorophyll in the first season, but negative insignificant with carbohydrates ,phenol and chlorophyll in the second season . Results revealed that the activities of antioxidant catalase enzymes (CAT) increased in leaves under insect infestation stress .The responses of CAT activity in some tolerant varieties such as Sakha2 and Sakha4 for infestation by L. trifolii and Empoasca spp. the highest activity of peroxidase enzymes (Pox) was observed in the tolerant varieties such as Sakha2 and Sakha4 varieties which possessed the highest tolerance to infestation stress among the 6 varieties for L. trifolii and Empoasca spp.. CAT enzymes showed the highest rate of activity changes under infestation stress than of Pox activity. Population of L.trifolii larvae correlated insignificantly positive with catalase and peroxidase enzymes in the first season, while positive significant with catalase and negative significant with peroxidase enzymes in the second season. Population of Jassids showed negative significant correlation with CAT and POX in the first season, while negative nonsignificant in the second season.