The population density of the honeydew moth (HM), Cryptoblabes gnidiella Mill. (Lepidoptera: Pyralidae) and its associated natural enemies was estimated in neglected (without chemical control treatments) orchard cultivated with mango trees (Mangifera indica L.), located at Shirben district, Dakahlia governorate, Egypt. The obtained results showed that this pest was recorded only at the height of 2.5±0.5 meters and was not at the height of 5.5±0.5 meters from the ground. The population of C. gnidiella had three peaks of abundance annually. During the two seasons of study, the anthocorid predator, Orius sp. was mainly associated with C. gnidiella population. In addition, an endo-parasitoid species was firstly observed on C. gnidiella larvae, namely, Tachina larvarum (Order: Diptera, Family: Tachinidae).Orius sp. exhibited three peaks of seasonal abundance annually. The total number of collected predator showed high significantly positive correlation with the average population density of the prey in the first and second years (r = 0.51** and 0.63**). The population of T. larvarum exhibited four peaks of abundance annually. The percentage of parasitism all over the season averaged 13.2±3.2 and 14.3±5.01% during 2016 and 2017, respectively. Statistical analysis indicated that there were significant positive correlations between populations of C. gnidiella and its parasitoid during the first (r = 0.65**) and second (r = 0.79**) seasons. Life and fertility tables of C. gnidiella reared on mango inflorescences were conducted under laboratory conditions. The developmental time of the egg, larvae and pupal stages lasted 4.1±1.8, 14.4±0.6 and 10.7±0.9 days respectively. The generation time, the net reproductive rate (R_O) and intrinsic rate of increase (r_m) were 35.97 days, 29.03 females/female and 0.04 female/female/ generation.