A field experiment aiming to study the effects of different irrigation systems and different volumes of water and their interaction between irrigation systems and volumes of water on growth, yield and quality of Hassawi muskmelon cultivar plants was conducted during two successive seasons (1999 and 2000). The four irrigation systems (drip, 15 cm and 25 cm sub- surface and surface irrigation) were applied to the Hassawi muskmelon cultivar plants with the two volumes of water 100 % (976 mm) and 75 % (710 mm) of field capacity. The results showed that using 15 cm sub- surface irrigation system was in favour for producing the best fresh weight/ plant, dry/fresh ratio weight and leaf area/plant, number of fruits /plant, fruit diameter, total yield and TSS %, while the treatment of using surface irrigation system gave the highest values for plant height, number of branches /plant, fruit height and fruit weight. However the treatment with 100% of field capacity gave the highest values for fresh weight/ plant, plant height, leaf area, number of branches/plant, number of fruits/plant, fruit diameter and total yield. The interaction between volumes of water applied and irrigation systems produced the highest values for fresh weight , dry/fresh  weight ratio, fruit height and total yield by using 100 % of field capacity with 25 cm sub- surface system.                 Finally it is possibly suggested that 25 cm sub- surface irrigation with 100 % of field capacity could be useful for enhancing the Hassawi muskmelon cultivar growth and fruit yield under Al-Hassa Oasis conditions.