This study was conducted during the 2019/2020 and 2020/2021 seasons at one of the agricultural nurseries in Dakahlia Governorate, Egypt to recognize how ground treatments and foliar application with some plant growth stimulants influenced the growth, chemical composition, and oil yield of Italian basil. The experimental plan for each ground treatment of vermicompost: clay soil at two rates (25:75 and 50:50%) (1:3 and 1:1v/v) in a separate experiment that used a randomized complete block design with four replications. Thirteen foliar spraying treatments using some plant growth stimulants were used as follows; control treatment, spraying plants with yeast extract at 2, 4, and 6 g/L, seaweed extract at 20, 40, and 60 %, chitosan at 500, 750, and 1000 ppm and vermicompost tea at 250, 500 and 750 ml/L. Growing Italian basil in media consisting of 25 % vermicompost: 75 % soil performed better than other media consisting of 50 % vermicompost: 50 % soil, which produced the highest values of all studied traits. The highest values of all studied traits were formed from foliar spraying Italian basil plants with chitosan at 750 ppm. It can be concluded that using growing media consists of 25 % vermicompost: 75 % clay soil in addition to foliar spraying Italian basil plants with chitosan at 750 ppm or vermicompost tea at 750 ml/L to enhance the growth and chemical composition and oil percentage of Italian basil (Ocimum basilicum L. var. Genovese) under the environmental conditions of Dakahlia Governorate, Egypt.