This work was carried out to study the effect of spermidine and ethryl on growth, yield and chemical composition of wheat (Triticum aestivum L.) plants grown in sandy soil at Kafr-Hakim, Giza, Egypt, during two successive seasons 1997/98 and 1998/99.                 The data indicated that spraying wheat plants with spermidine or ethryl had a positive effect in most cases on growth parameters, the maximum values were obtained with spermidine at 150 and 200 ppm.                 Spraying wheat plants with the spermidine at 150 and 200 ppm gave the highest economic yield of grain and 1000-grain weight. Spraying plants with spermidine at 100 and 150 ppm attained significant increases in straw yield.                 Application of spermidine or ethryl treatments in general decreased protein content and total soluble sugars, while increased total sugars and non soluble sugars. On the other hand, using spermidine at 150 and 200 ppm and ethryl at 100 g/fed had an obvious stimulating effect on  phosphorus percentage in wheat grains. The results has been interpretted by the correlation coefficient between wheat plants characters under spermidine treatments which indicated that grain yield was positively and significantly correlated with plant height and spike weight, while positively nonsignificantly correlated with tillers number, spike length, flag leaf area and 1000-grain weight. Under ethryl treatments  grain yield was negative and nonsignificantly correlated with tillers number, spike length, straw yield and total soluble sugars. On the other hands positive and nonsignificant, correlations of grain yield was obtained with other characters under ethryl treatments.