The present investigation was carried out at the Nursery of the Forestry Department, Horticulture Research Institute, Agricultural Research Centre, Giza during the two successive seasons of 1999/2000 and 2000/2001 to evaluate the vegetative growth of some Mahogany species adapted in Egypt ; i.e., Swietenia macrophylla. King, Swietenia mahogani (L.) Jacq., Khaya ivorensis A. Chev. and Khaya senegalensis (Desr.) A. Juss. Also, the percentage of seed germination for each genotype was calculated. Moreover, biochemical analysis was done, in seeds of each studied species, using SDS- polyacrylamide gel electrophoresis separation of total soluble protein method for genetic identification and differentiation among Mahogany species under investigation.                 The obtained results indicated that the four studied genotypes of the Mahogany family (Meliaceae) showed significant differences in the percentages of seed germination as well as in their vegetative growth attributes (plant height, number of developed leaves per plant, total leaf area per plant, shoot fresh weight per plant and shoot dry weight per plant) in both studied seasons and Khaya senegalensis exceeded significantly all other genotypes in this respect. Data on biochemical analysis revealed that, polyacrylamide gel electrophoresis separation of total soluble proteins can be used as a genetic finger print for identification, differentiation and comparison among the four different species as well as between the two different genera of the Mahogany family under investigation.