Ten promising advanced durum wheat lines derived from National Wheat Program and five cultivars(BaniSweif 1, BaniSweif 5, BaniSweif 6, Sohag 4, and Sohag 5) were evaluated at the Experimental Farm of Sids Agricultural Research Station, Agriculture Research Center (ARC), Egypt, throughout the twogrowing seasons 2018/2019 and 2019/2020. The studied genotypes were grownunder normal conditions and five combinations of heat and water stress conditions. The combined analysis of variance demonstratedsubstantialvariations between thetreatments, genotypes, as well as their interaction for all the studied traits.In addition, resultsrevealed thatchlorophyll content,days to heading, grain yield, and its components were substantiallydiminishedvia delaying the date of sowing as well as water stress conditions. Stressed conditions (T6) reduced the Spikes m^-2 number, kernelsspike^-1number, 1000 kernels weight, and grain yieldby 42.13, 43.75, 21.04, and 48.15% respectively, compared to normal conditions (T1). The mean performance of the genotypes showed thatthe genotypes that exhibited the highest productivity were Sohag 5, Line 1, Sohag 4, and Line 2.GGE biplotillustrated thatthe most stable genotypes with the greatest grain yield were Sohag 5, Line 1, Sohag 4, Line 3, Line 6, and Line 10, while, Line 2 and Bani Suef 5 were the least stable genotypes across the studied environments.