This research was conducted in the two successive seasons of 2019-2020 and 2020-2021 in a private farm at Abu Al- Matamir city, Al-Behiera Governorate, Egypt, under open field condition, with surface irrigation system. The aim was to study the influence of seaweed extract levels and gibberellic acid levels as well as their interactions on globe artichoke plants performance, cultivar ‘Balady' such as vegetative growth traits, yield and head chemical elements. The experiment was carried out in a split plot system in a Randomized Complete Blocks Design (RCBD) with three replicates. The experiment contained 16 treatments as combinations between seaweed extract with 4 concentrations (0, 1000, 2000 and 3000 mg/l) as main plots, and GA₃ with 4 concentrations (0, 35, 75 and 105 mg/l) as the sub- plots. Explants were soaked in each solution for 10 min. The obtained results indicated that soaking explants in seaweed extract singly or GA₃ singly recorded the highest values of survival rate%, number of leaves/plant and number off-shoots/plant, early and total yield expressed in average weight of fruit g/plant and number of fruit/plant as well as N, P and K of head at 3000 and 105 mg l^-1, respectively. Also, the combined treatment between 3000 mg l^-1 seaweed and 105 mg l^-1 GA³ brought about the highest average values of the examined traits and might be regarded as the recommended treatment for growing globe artichoke plants with a high yield and good quality under the similar conditions of the study.