The present investigation was carried out during the two successive seasons of 2002 and 2003 on mature trees of Canino, Amal and Perfection apricot cultivars. It aimed to study the effect of different pollination treatments on yield and fruit quality of the studied cultivars, to evaluate the degree of self compatibility and role of cross pollination in improving the production of these cultivars. The pollination treatments used in this study were as follows: Open pollination, Bagging only, and Cross-pollination as follows:-(A) Perfection (♀) X Canino (♂).(B) Perfection (♀) X Amal (♂).(C) Perfection (♀) X {Canino+Amal} (♂)).The results obtained could be summarized as follows:Canino and Amal cultivars succeed to give higher than 20% fruit set after Bagging only treatment. While, Perfection cultivar produced lower than 2% fruit set in the two seasons of study. Thus, Canino and Amal are considered self-compatible (fertile) cultivars. While, Perfection is considered self-incompatible (sterile) cultivar.Canino and Amal cultivars produced higher percentages of fruit set with open pollination than that of bagging only treatment. In addition, cross-pollination for Perfection cultivar by Canino pollen grains produced higher percentage of fruit set. While, the cross-pollination by Amal pollen grains gave lower percentage of fruit set than those of the rest pollination treatments in the two seasons of study. Calculated values of fruit weight, flesh weight, stone weight, fruit length, fruit diameter, fruit firmness were higher after open pollination for Canino and Amal cultivars and cross pollination for Perfection cultivar by Canino pollen grains than those of the rest pollination treatments. Open pollination treatment for Canino and Amal cultivars and cross-pollination for Perfection cultivar by Canino pollen grains increased fruit total soluble solids and ascorbic acid (vitamin C) as well as, the same treatments increased the (T.S.S./acidity ratio) than those of the other pollination treatments. Fruits produced from open pollination for Canino and Amal cultivars and cross-pollination for Perfection cultivar by Canino pollen grains were higher in total sugars percentage and carotene than those of the other pollination treatments. However, there were no significant differences among all treatments in fruit total phenols content.