This study was carried out during the two successive seasons, 2004 and 2005 in an attempt to find out the optimum number of buds to be left on vines of the newly introduced Melissa Seedless grape cuitivar which realizes to get the highest possible yield with the best fruit quality. 5 Year-old-uniformed vines were chosen and pruned to 6 different levels of bud load, 84, 98, 112, 126,140,154 budsfvine. 14 buds per cane leaving fixed for all treatments. The results showed that increasing bud loadlvine resulted in an increase in the number of buncheslvine, yield/vine and acidity of the juice. On the other hand, percentage of bursted buds, fertility and bunch weight, berry weight, siZe, length and diameter, wood ripening coefficient, weight of prunings, cane carbohydrate content. T.S.S and T.S.Sfacid ratio were found to decrease as the bud load was increased. Berry shape index and compactness coefficient were unaffected. The optimum number of budsfvine to be left at pruning time for Melissa Seedless Cv. ranged between 112, 126 budsfvine.