In this study, investigate the influence of foliar spraying by antioxidants (salicylic, ascorbic, oxalic, boric and nicothinic acid) at rate of 150/300/450 ppm on growth, flowering, chemical and quality composition of chrysanthemum (Dendranthema grandiflorumRam) plant during winter seasons of 2018-2019 and 2019-2020. Salicylic acid at 450 ppm was more successful than most of the other treatments for increasing plant height, number of branches/plant, fresh and dry weight as well as flowering traits as number of flower/plant, also, pigments content of leaves (total chlorophyll and carotenoids) , N, P and K (%), total carbohydrates (%), phenol(mg/100g DW), but decreased proline content. While, the lowest values of all parameters were observed with the control treatment (sprayed with water) except proline content recorded the highest value during both seasons of the experiment.