Soil solarization as a clean natural physical source was proposed in this trial to control cantaloupe damping-off and wilt diseases affecting cantaloupe (Cucumis melo var reticulatus)  produced for export and local consumption, such diseases in the experimental area at Qena governorate, Isna region in upper Egypt caused by pathogenic soilborne fungi mainly Fusarium spp. and Rhizoctonia solani. In this soil solarization experiment to control these pathogens, three types of polyethylene (PE) plastic sheets were used as soil mulching for about 7 weeks during summer (July-August-September), started on  July 20^th. Treatments concerned, UVI sheets of 200 micron in thickness; 60 micron transparent, 30 micron black and un-covered control treatment for two growing seasons of 2003/2004 and 2004/2005. Meteorological data were recorded during solarization period. The used cantaloupe F1 hybrid was Ideal. Data indicated that the 200 micron transparent plastic sheets treatment followed by the 60 micron mulch gave better results which reflected on cantaloupe yield and fruit quality beside the parameters of soil infection with mentioned pathogens i.e., damping-off of cantaloupe seedlings %, mortality % at the end of harvesting period