A pot experiment was carried out at Faculty of Agriculture Farm, Al-Azhar Univ, Assiut, during the two successive seasons 2018 and 2019 aiming to study the effect of three rates of saline water at (0.0, 30 mM and 60 mM Nacl+Cacl₂) and foliar spraying by biostimulants namely, (control, pigeon manure extract at 4g/L, pigeon manure extract at 8g/L, yeast extract at 4g/L, yeast extract at 8g/L, licorice extract at 4g/L and licorice extract at 8g/L ) as well as, their interaction on growth, yield and chemical constituents of hot pepper var. (Fire Bomb).The obtained results showed that both concentrations (30 mM and 60 mM Nacl+Cacl₂) caused a significant reduction in all vegetative growth, yield components and chlorophyll content measurements of hot pepper. While, there was a significant increase in capsaicin content as a result of concentrations (30 mM and 60 mM Nacl+Cacl₂) over control. With regard to foliar spray with biostimulant treatments at all concentrations, these treatments led to significantly increase in growth parameters, yield components, as well as, total chlorophyll content and total capsaicin content. The high concentration of pigeon manure extract and licorice extract at 8g/L gave the highest values of these previous traits over control. On the other side, foliar spray with these studied biostimulants at all concentrations caused a reduction in proline content, Na and Ca % in leaves. Concerning to the combined between the two examined factors, foliar spray by biostimulant treatments alleviated adverse effect of salt stress, in most cases.