Two field experiments were conducted under Egyptian conditions at Kaha Vegetables Research Farm, Horticulture Research Institute, Agriculture Research Centre to study the effect of the high nitrogen and potassium levels and two growth regulators, Cytokinin at 2.5 ppm and Gibberellic Acid (GA₃) at 100 ppm on the growth and seed yield of garlic (Allium sativum L.) cv. Sids 40. The obtained results showed that increasing nitrogen and potassium fertilizer up to 150 % NK. of the recommended rate (120 kg N + 72 kg K₂O fed^-1),  significantly improved most studied growth traits (plant length, number of leaves, leaf area, total fresh weight, total plant dry weight), bulb characters, chemical constituents, yield, and yield components. Moreover, 150 % NK combined with GA₃ + CPPU foliar spraying resulted in the highest average bulb weight, average glove weight and bulb. The obtained results confirm that garlic seed yield could be improve by N, K nutrition and foliar application of GA₃ and CPPU.