Two field experiments were conducted at the Experimental Station Farm in Kalapsho and Zaian region, Fac. of Agric., MansouraUniv. during 2004/2005 and 2005/2006 seasons to determine the effect of nitrogen, phosphorus and potassium fertilizers levels as well as their interactions on growth, seed yield and its components as well as quality of oil seed rape (canola). Pactol cultivar under conditions of newly reclaimed sandy saline soils as in Kalapsho and Zaian region, Dakahlia Governorate was used. The main results of this study can be summarized as follows: Increasing nitrogen fertilizer levels from 45 to 60 and 75 kg N/fed significantly increased plant height, number of primary and secondary branches/plant, number of pods/plant, pod length, number of seeds/pod, 1000-seed weight, seed yield/fed and in both seasons. However, oil % markedly reduced by increasing nitrogen levels. Phosphorus fertilizer levels markedly increased all studied characters in favour of  30 kg P₂O₅/fed in both seasons, except for oil % only in the first seasons. Increasing potassium levels up to 24 kg K₂O/fed significantly increased plant height, number of primary and secondary branches/plant, number of pods/plant, pod length, number of seeds/pod, 1000-seed weight, seed yield/feddan and oil % in both seasons. Except for number of secondary branches/plant in the first season, 1000-seed weight in the second season and oil percentage in both seasons where the differences between K levels did not reach the level of significance.   It can be concluded that using NPK fertilization at 75 kg N + 30 kg P2O5 + 24 kg K2O/fed in order to maximizing seed and oil yields of canola under the environmental conditions of Kalabsho and Zayian district – Dakahila Governorate.