Six fungal species, namely: Alternaria alternata, Botrytis cinerea, Fusarium rousm, F. tricnictum, Stemphylium botryosum and Thielaviopsis sp. were isolated from lettuce leaves collected from Riyadh markets during summer months in 2005. The fungal isolates were examined for their ability to produce  five extracellular enzymes, namely: amylase, lipase, protease, cellulose and phenoloxidase, on solid media. They were also  examined for  production of one endoenzyme which is phosphatase. The results showed that all isolates were able to produce amylase though with variable magnitudes; the highest amylase activity was displayed by F.rousm followed by F. tricnictum.  Concerning lipase  activity Theilaviopsis sp. and F. rousm showed the highest potential; A. alternate and F. tricnictum came next, whereas   B. cinerea and S. botryosum  failed to produce lipase.Regarding protease enzyme, only two isolates (A. alternata and F. rousm) were able to produce the enzyme. The present study showed also that A. alternata followed by B. cineria, F. rousm and S. botryousm were able to produce cellulase, whereas the other two fugal species did not display any cellulase activity.  On the other  hand, all isolates, except B. cinerea  do not produce phenoloxidase. Meanwhile,  the  largest  colonial diameter on agar media was  yielded   by   F .rousm followed by S. botryosum A. alternata, F. tricnictum, and B. cinerea,  respectively. This investigation also showed that the cell-free extracts of all the fungal isolates tested appeared to  catalyze the phosphate ( adenosine 5-monophosphate, AMP) hydrolysis; and the following sequence was displayed  for acid phosphatase activity of the experimental fungal isolates:  A. alterna, B. cinerea , S. botryousm, Theilaviopsis sp.,  F.  tricnictum andF. rousm, in descending  order, respectively.