Maximizing use of water unit is one of the most important approach of sustainable agricultural development from agricultural policy-makers view around the world in the past and the future. Also, agriculture sector actively consumes large amounts of fresh water share in Egypt. Agricultural drainage water represents a significant percentage of water if it is reused again by raising its quality. So, this could be obtained by using magnetic technology (water/filed) as a means of mitigation lack of water by reusing agriculture drainage water in vegetable crops irrigation like tomato and studied plant productivity under these conditions. The objectives of this research were to evaluate the efficiency of magnetized drainage water and some anti-stressors on tomato plants behavior under Delta region conditions. The data presented in this paper are the results of two field experiments and it was observed that irrigation magnetic agriculture drainage water superior untreated plants in their effects on most of studied parameters. Concerning anti-stressors treatments, melatonin followed by glycine betaine recorded the best effects on plant growth, chemical composition, enzymes activity as well as yield and fruit quality parameters in both seasons.  However, plants irrigated with drainage water only achieved the lowest values of all parameters as a result of salinity stress except fruit quality. The most concluded treatment of the superior positive effect on tomato plant productivity was irrigation with magnetized drainage water with foliar spray with melatonin, also it may be considered as the best option to save water under its scarcity and limited sources.