The present study was conducted at Sakha Agricultural Research Station's Experimental Farm to evaluate six wheat genotypes during 2017/18 and 2018/19 wheat growing seasons under normal irrigation (five irrigations) and reduced irrigation (only one irrigation after the establishment). A randomised complete block design with nine replicates was the experimental design. Two stress tolerance indices were calculated to differentiate the high yielder and water deficit tolerant wheat genotypes. Results showed that the irrigation effect was highly significant for all studied characters, except for number of kernels spike^-1. The mean values of all studied characters in the normal irrigation were higher than those recorded in the reduced irrigation, except for number of kernels spike^-1 and 1000-kernel weight. There were a highly significant differences among genotypes for all the studied characters. The best cultivar was Misr 2 which recorded the highest values for grain filling rate, number of spikes m^-2 and grain yield with a significant differences compared to the other studied genotypes. Two susceptible/tolerance indices indicated that the three genotypes namely Cham 4, Sakha 93 and Vorobey were identified as stress tolerant genotypes and the genotypes Cham 4 had the higher grain yield as well. Accordingly, it was recommended to be used in wheat breeding programs to transmit tolerance genes to the commercial cultivars for reduced irrigation.