The present study was carried out for the comparison of six pomegranate cultivars namely:  Manfalouty, Nab El-Gamal, Wardy, Araby, Badr and Tahrir grown at the experimental farm of the  Hort. Res. Instit., station at Seds, Beni- Suef Governorate of middle Egypt region during the two growing seasons of 2007 and 2008.The present study included the different polymorphism variances as ;  vegetative  growth, flowering, yield, fruit quality and rooting ability of the six pomegranate cultivars. In this respect, Manfalouty and Tahrir cultivars were superior in most of vegetative growth characteristics. On the other hand, Badr cv. had the lowest values in most of these growth characteristics. The highest percentage of perfect flowers / tree was recorded for Araby and Tahrir cvs. and the lowest one was for Nab El-Gamal cultivar. Manfalouty and Wardy cvs. gave higher percentage of fruit set while Badr cultivar recorded the lowest values. Moreover, Nab El-Gamal and Manfalouty exhibited the highest yield (kg / tree), fruit weight, length, diameter & volume and juice volume while Badr cv. gave the least ones. The highest percentage of fruit grain was in Tahrir cultivar. As for fruit juice chemical characteristics (total acidity; total soluble sugars; vitamin (c); ascorbic acid; total anthocyanin and tannins), in general, the best cultivars were Manfalouty, Nab El-Gamal, Wardy and Tahrir. Cuttings of Badr and Tahrir cultivars gave the highest rooting percentage with tallest root while Nab El-Gamal had the highest number of roots in both experimental seasons. It is worthy to mention that, it can be recommended with Nab El-Gamal, Manfalouty, Wardy and Tahrir cultivars
( the yield more than 30 kg/tree) to be planted in Beni-Suef Governorate representing the Middle Egypt region and are preferable than Badr and Araby pomegranate cultivars.