This investigation was carried out during the two successive seasons of 2005/6 and 2006/7 to study the response of Hindi BeSinara cv. mango trees to zinc and boron as well as the combination (Zn+B) as soil and/or spraying application treatments. The chosen trees were 10-year-old grown in loamy soil of a private orchard at Beni-Mazar, Minia Governorate. The trees were supplied with N, P and K at rates of 1000, 400 and 1000 g/tree/year. Zn at 250 g and Boron at 500 g and its combination (Zn+B) were added as soil application. Spraying application with 150 g Zn and 300 g B and its combination (Zn+B) were occurred at monthly intervals (3 equal doses) from March to May. The obtained results revealed that all treatments of Zn and B and the combination of them did not affect growth of trees. Sex ratio, fruit length, fruit diameter and L/D ratio, total acidity and leaf contents of N, P, K, Ca, Mg, Fe, Mn and Cu showed insignificant differences as compared to control. However, fruit set, yield, fruit weight, pulp and peel weight, TSS, TSS/acid ratio, leaf Zn and B contents were significantly improved by Zn and B treatments. In addition, B treatments were more effective than Zn treatments. The combination of Zn+B treatments was the best treatment and spraying application was superior in comparison to soil application.