The present investigation was carried out during the seasons of 2006 and 2007 to study grafting operations of Thompson seedless (TH), Superior (SU), Flame seedless (FL) and king ruby (KR) scions onto four grapevine rootstocks namely, SO4, 1103 Paulsen (1103 P), Teleki 5C (5C) and 140 Ruggeri (140 Ru). It was aimed to estimate the degree of graft compatibility between the partners used to create graft combinations. Such estimation was based on a group of parameters known to play an important role in the field of graft compatibilities. They were included the calculation of grafting success percentage, the measurement of certain characteristics usually use to represent the whole growth of graft combination, the determination of certain chemical and biochemical constituents in scions leaf along at the graft union line. Furthermore, an anatomical microscopic examination on tissues from the graft union was carried out. All these studies were to be used as criteria for estimating the degree of graft compatibility among scions and rootstocks tested in this study. Consequently, it could pointed to the best rootstock successfully combined with the used scions.