Two field experiments were carried out at Shandaweel Agricultural Research Station (latitude of 26 33° N and longitude of 31 41°E), Sohag Governorate, Egypt in 2018/2019 and 2019/2020 seasons to study efficacy of some integrated weed control treatments (removing or burning cane trash; hoeing and Ready Peck, Clomdi, Lumax, Garlone herbicides) on yield and quality of sugarcane 1^st ratoon of G.2003-47 variety (Giza-3). A randomized complete block design in a split-plot arrangement with three replications was used. The results showed that the removal of plant cane trash out of the field resulted in significant increases in millable cane height, number of millable canes, cane and sugar yields/fed of the 1^st cane ratoon crop. However, cane trash treatments had insignificant effect on weed traits, millable cane diameter and juice quality. The applied herbicides and hoeing (twice) negatively and significantly affected fresh, dry weight of both grassy and broad-leaved weeds and their total weight, compared to un-weeded plots. The applied herbicides and hoeing appreciably increased millable cane height, number of millable canes, sucrose%, sugar recovery%, cane and sugar yields. Hoeing was the most effective in weed eradication, resulting in higher sugarcane traits, compared with the other treatments. The effects of interactions among the studied factors on sugarcane and/or weed traits were discussed. Under conditions of the present study, the removal of trash of the plant cane crop out of the field, with hand hoeing twice can be concluded to attain the highest cane and sugar yields of 1^st ratoon cane crop.