The present study was carried out on Jojoba plants [Simmondsia chinensis(link)Schneider] during two successive seasons, i.e. 2007 & 2008 . Two experiment were designed for the possibility of using leafy soft stem cuttings for propagation of jojoba plants vegetatively . In the first experiment date of collecting leafy stem cuttings, i.e. April, July and November were tested, the cuttings were dipped in NAA or BA either alone or in combination with TIBA.. In the second experiment, the cuttings were dipped in IBA 3000 ppm + TIBA100 ppm and Leafy stem cuttings were planted in different media to examine their influence on rooting and vegetative growth. The obtained results showed that dipping of Mid April cuttings in IBA 3000ppm+TIBA 100 ppm solutions significantly increased all rooting and growth measurements, i.e. rooting % numbers and length of developed roots, and average length ,diameter of main shoot and total number of branches compared to the other treatments or the control. With regard to media, it was found that perlite + vermiculite was  most suitable since numbers of roots/ cuttings, root length, or root length, or rooting % as well as survival % and length, diameter and number of leaves/ transplant were more than using other media. Therefore, it could be recommended to using soft stem leafy cuttings from selected jojoba trees during April for vegetative propagation after dipping in TIBA at 100 ppm + IBA at 3000 ppm and growing in perlite + vermiculite media. The anatomical study for stem cuttings of jojoba plant was found that was originated from the cambial zone. The cells of cambial zone were divided to from root primordial and continued to develop.