A pot experiments was carried out to investigate the role of some antioxidant materials (presoaking and foliar spray ) in alleviation the harmful effect of biotic stress Fusarium graminearum or Bipolaris sorokiniana on wheat plant. Applied antioxidants decreased pre and post-emergence damping off, leaf infected percentage and  leaf disease severity, fungi transmission from root, stem and grains of wheat plants growing under infected soil with Fusarium  graminearum or  Bipolaris  sorokiniana in comparing with untreated plants growing in the same soil. However, grown infected soil  enhanced survived seedlings percentage , emergence percentage of wheat plants with Fusarium  graminearum or  Bipolaris sorokiniana compared with untreated plants grown under same condition . SWE and Zn were more effective comparing with other antioxidants in both Fusarium  graminearum  or  Bipolaris  sorokiniana. Applied antioxidants in high concentration were more effective than other concentrations  in this respect.