A field experiment was carried out in sandy soil in EL-Kattba, Manofya Governorate Egypt, during the successive growing seasons of 2007 and 2008 on Jerusalem artichoke. The main objective of this investigation was to study the effect of cultivars (Local and Fusaeu ) and two planting dates(15^th April and 15^th May ) with two harvesting dates (15^th Nov. and 15^th Dec.) on vegetative growth , total yield , marketable yield and its components of Jerusalem artichoke. The results indicated that Local cultivar showed higher foliage (plant height) than Fusaeu, but there was no significant effect on number of lateral branches / plant .In addition, Local cultivar showed significant increases in total yield and its components and tuber contents of dry matter, inulin and total sugar compared with Fusaeu . Concerning planting dates, results showed that the planting on 15^th of April increased significantly the vegetative growth parameters, total yield and its components, and tuber contents of dry matter, inulin and total sugar in comparison with planting on 15^th May. Regarding the harvest date, data revealed a positive effect of tubers harvest on 15^th of Nov. on total yield and its components, and tuber contents of dry matter, inulin while total sugar decreased compared with tubers harvest on 15^th Dec.   The interactions between cultivars and planting dates showed that Local cultivar and planting on 15^th of April increased significantly the vegetative growth, total yield and chemical constituents of tubers under sandy soil conditions .Also, Local cultivar tubers harvested on 15^th of Nov. produced higher significant total yield and its components, and tuber contents of dry matter, inulin while total sugar decreased compared with tubers harvested on 15^th of May. The interactions among cultivars, planting dates with harvesting dates, showed that the Local cultivar planted on 15^th of April and harvested tubers on 15^th of Nov. produced higher significant increases in yield parameters and chemical constituents of tubers under sandy soil conditions.      Finally, it could be concluded that the optimum planting dates of Jerusalem artichoke (Local cultivar) was on 15^th of April and the ideal harvesting date was on 15^th of Nov. for a highly production and quality of tubers under sandy soil.