Interactive effects of (proline, ascorbic acid, reduced glutathione and salicylic acid) either alone or in combination with 50 and 300 mM NaCl on seedling growth, lipid peroxidation and electrolyte leakage of two phenotypes {salt-sensitive (cv. Giza 716) and salt-tolerant (cv. Giza 843)} of broad bean after priming were investigated. Treatment of the germinating broad bean seeds of both cultivars with 50 and 300 mM NaCl induced progressive significant decrease in fresh mass, dry mass, water content, relative growth index (RGI), relative growth rate (RGR), length of radicle and length of plumule but induced significant increase in lipid peroxidation and electrolyte leakage after priming, 7 and 14 days of germination .    On the other hand,  addition of the optimum concentrations of proline (Pr), ascorbic acid (ASA), reduced glutathione (GSH) and salicylic acid (SA) either alone or in combination with 50 and 300 mM NaCl, induced significant increase in all growth parameters and showed a progressive significant decrease in electrolyte leakage determined in both cultivars after priming, 7 and 14 days of germination. Maximum significant improvement being operative with the optimum concentration of SA than the other used osmolytes. The present results are discussed in relation to applicability of the optimum concentrations of four osmolytes to two salt-sensitive and salt-tolerant broad bean seedlings.