This experiment was conducted at the private farm of Mr. Mohamed El-Soony under the official supervision of Faculty of Agriculture, Minia University and Sids Horticulture Research Station, Agricultural Research Center, Giza, Egypt, during the two successive winter seasons of 2007/2008 and 2008/2009 in calcareous sandy soil of the new reclaimed area in west Beni - Suef conditions under a drip irrigation system. The objective of this study was to determine the effect of plant density on growth, yield and yield components of four garlic genotypes. Genotypes were grown in the field at two plant densities (60 and 90 plants / m²). As plant density increased, total fresh and cured yield increased from 7.99 to 10.37ton per Fed., and from 4.52 to 5.66 ton per Fed., respectively. Fresh weight of individual plants, bulb fresh weight, bulb dry matter percentage, and cured bulb weight and bulb diameter characteristics was decreased significantly as population density increased. No significant differences among the tested treatments for number of cloves per bulb. Eggaseed 1 had the highest total yield, whereas the Egyptian cultivar had the lowest. In addition, there were significant interactions between plant density and genotypes for the total fresh and cured yield. Based on the obtained results it could be concluded that for maximizing garlic yield, clone St 133 should be grown at 90 plants m² under fertigation system in the calcareous soil in the west of Beni Suef and similar conditions.