A field study was conducted during 2010 and 2011 rice growing seasons at Rice Research and TrainingCenter, Sakha, Kafr El-Sheikh, Egypt to detect the influence of integrating rice seeding-bed techniques and weed control on weeds and rice yields of drill-seeded rice.     The application of stale-bed technique including spraying glyphosate before drilling rice seeds significantly reduced weed dry weight while increased number of tillers, number of panicles /unit area and rice grain yield. All tested herbicide treatments (thiobencarb followed by penoxulam, thiobencarb alone at a high rate, penoxulame at a high rate and bispyribac alone) greatly suppressed dry weight of weeds in drill-seeded rice while significantly increased number of tillers, panicles/m² and rice grain yield/ha. Thiobencarb followed by penoxulam achieved the best weed control and the highest yield followed by penoxulam alone All weed control treatments were significantly efficient against weeds under the stale-bed technique even with the untreated check plots. Using thiobencarb followed by penoxulam achieved the highest efficiency against weeds and the highest number of tillers, panicles/m² and grain yield of drill seeded rice under both stale-bed and conventional techniques.