The effect of some organic soil amendments such as cattle, poultry and sheep manures and four insecticides nudrin 90%, selecron 72%, tracer 24% and vertmik 1.8% and their interaction on sugar beet productivity and the infestation rate of beet fly, P. mixta were carried out at Damanhour and Nubariya regions under field conditions. The results raveled that population density of P. mixta, root yield, top yield, sugar yield and quality parameters were significantly affected by all organic manures and insecticides treatments. Generally, the highest accumulative larvae of P. mixta recorded with poultry manure followed by cattle manure and sheep manure in Damanhour and Nubariya regions. Also, in two locations poultry manure gave remarkable results in suppression in root, top and sugar yields as well as sucrose and purity% compared with cattle and sheep manures. All tested insecticides in the two locations significantly reduced the population density of beet fly, P. mixta on sugar beet plants in comparison with the cheek treatment. Sugar beet plants sprayed by selecron 72% the reduction% of P. mixta population increased with the time elapsed treatment. Selecron 72% was the most effective against P. mixta followed by tracer 24%, vertmic1.8% and nudrin 90%. Also selecron 72% was ranked the first in root and top yield, however, sugar yields gained the highest value by tracer treatment. Top, root and sugar yields, T.S.S.% and purity% were significantly affected by the interaction between tested organic manure, and insecticides. The highest top, root and sugar yields were obtained with (cattle manure x selecron 72%), (poultry manure x tracer 24%) and (cattle manure x tracer 24%) treatments, respectively. However the highest values of T.S.S. and purity% were obtained with (poultry manure x tracer 24%) treatment.