For facing acute problem of fresh water scarcity in the future to face the increasing population problem and also for cultivating newly reclaimed lands. So, two field experiments were conducted in the open field at farm Meat Salseil near Mansoura, City Dakahlia Governorate, Egypt during two successive early summer seasons of 2012 and 2013 on clay loam soil to investigate the effect of two treatments of irrigation intervals (10 and 20 days) and four treatments of foliar application from antitranspirants (control, Kaolin, Potassium silicate and dyriton ) as well as their interactions on growth, fruit quality, yield and its components of eggplant (Solanum melomgena L.) c.v Black Beauty. The experimental design was a split plot, where irrigation intervals were in the main plots and antitranspirants source allocated in the sub plots in a randomized complete block design with three replications. The results obtained from this work could be summarized as follow: The effect of interaction between irrigation intervals and foliar antitranspirants had significant effect on all plant growth parameters during both seasons. The foliar application of antitranspirants, significantly enhance fruit quality compared with control treatment except acidity in the 1st season. As soon as spraying dyriton (4 %) under short irrigation intervals (10 days) recorded the highest values of T.S.S % and V.C. Also, the obtained results showed that application of antitranspirants were significantly increased on the most of yield parameters. The highest values were recorded with sprayed dyriton 4 % compared with the other treatments. The interaction between irrigation intervals (10 and 20 days) and different foliar antitranspirants caused an increment on the most mentioned parameters of yield during both seasons. Generally, it could be concluded that the importance of determine the interactive effects between irrigation intervals and antitranspirants,  to find out the optimum combinations for maximum early, total yield and fruit quality. It was found that irrigation intervals under 10 days with 4 % dyriton sprayed as antitranspirants, had the best combination and it is recommended for eggplant grown under similar field condition in order to get higher economical yield.