A field experiment was carried out in Al-Mijar Al-Kabeer District, 25 km South of Misan Governorate, Iraq, during 2016/17 and 2017/18 seasons to study effect of spraying with Azolla extract‎ at 0, 20, 40 and 60% and NPK-fertilizers levels (60, 80 and 100% of the recommended doses "RD") on Egyptian wheat Sids 1cultivar productivity under new reclaimed soils. The experiment was applied according to split-plot design with three ‎replicates.‎The results showed that increasing concentration of the Azolla extract‎ resulted in an increase in most studied characters in both seasons. The increasing rate in grain yield was 57.37 and 51.71 % and in biological yield was 37.66 and 21.57 % for foliar spraying ‎with Azolla extract at 60 % compared with control treatment in the first and second seasons, respectively. Most studied characters gradually increased due to increasing NPK-fertilizers levels from 60 to 80 and 100% of RD and without significant differences between 80 and 100% in both seasons. As for the interaction between spraying ‎with Azolla extract levels and NPK-fertilizers levels, it was significant on spike length in 1st season only, number of spikes/m2, weight of 1000 grains and biological yield in both seasons. It can be stated that foliar spraying Egyptian bread wheat Sids 1cultivar with Azolla extract at 60 % alongside mineral fertilizing with 152.0 kg N + 42.8 kg P2O5 + 45.6 K2O ha-1 (80% of RD)  to preserve high productivity simultaneously reduce production costs and environmental pollution under the environmental conditions of Misan, Iraq.