Two field experiments were conducted in El-Serw Agricultural Research Station, ARC, during 2015/16 and 2016/17 seasons to study the possible integration between three sugar beet cultivars varied in its growth habitat: Glorius, Lilly and Cleopatra and six weed control treatments which are being: Goltix plus at 1.5 L/fad., Goltix  at 2 L/fad., Cross  at 2.5 kg/fad. as post emergence herbicides and Harness at 0.75 L/fad. as pre emergence herbicide in addition to hand hoeing twice and unweeded check on weeds associated with sugar beet productivity and its economic feasibility. The main findings showed that both Glorius cultivar suppressed weed growth at 120 DAS by 62.2 and 39.9%, accompanied with increasing sugar beet root yield by 28.4 and 32.6% and with Lilly cultivar by 19.1 and 14.0% reduction on weed growth and increased root yield by 34.5 and 17.0% in both seasons, respectively, compared than Cleopatra cultivar. On other hand, Cross herbicide as ready-made exceeded other herbicides and hand hoeing twice on controlling total weeds until 120 DAS by  85.5 and 71.6% and increasing sugar beet yield by 151.6 and 217.0 % than unweeded check in both seasons. The best integration between Glorius and Lilly cultivars both with application Cross herbicide from view point of weed control by 90.5 and 87.2%, respectively, in 2015/16 season and 88.7 and 71.4%, respectively, in 2016/17 season, respectively and increasing sugar beet root yield by 215.6 and 264.6%, respectively, in 2015/16 season and by 323.9% and 308.6, respectively, in 2016/17 season accompanied with increasing  farmer incomes