This study was conducted at Rice Research and Training Center (RRTC), of Farm Sakha - KafrelSheikh, Egypt, during the summer seasons of 2010 , 2011 and 2012 to investigate the combining ability of some parental lines in their crosses. Three cytoplasmic male sterile (CMS) lines as female parents and seven restorer lines as male parents were hybridized to produce 21 F₁ hybrids in a line x tester mating model (Kempthorne, 1957). The General and specific combining ability effects of the genotypes for the characters under study were estimated. The results showed that the characters were controlled by general combining ability (GCA) and specific combining ability (SCA) . The CMS and restorer lines showed favorable  effects for GCA of yield and yield components. The results indicated that most characters  were largely governed by additive gene action. finally, the hybrid combination IR69625A× Giza 179 could be used as a promising hybrid for early maturing and high yielding varieties.