Two field experiments were conducted during the two growing seasons of 2014/2015 and 2015/2016 at private farm, Sherbeen region, Dakahlia Governorate, Egypt, to evaluate the role of some biostimulants and lithovit with or without boron foliar application on potato growth and yield as well as some physiological and anatomical characters. Results revealed that foliar application of biostimulants and lithovit with or without boron application significantly increased potato growth parameters (i.e. Plant height, branch number per plant, shoot fresh and dry weights, and leaf area per plant), as well as the potato tuber number and total tuber yield per plant. Quality of potato tuber significantly increased with biostimulants and lithovit with boron application. The most effective treatment in this regard was seaweed extract plus boron fertilizer. It is recommended to spray potato plants twice at 50 and 60 days from planting with 500 mg/l seaweed extract plus 1000 mg/l chelated boron in order to attain the highest yield and quality.