Two field  experiments  were  carried out at  a Private Farm near Elzarka city, Damietta Governorate, during   the two successive summer growing seasons from march to November 2013 and 2014 to study the effect of organic manure treatments (control, 25 m³/fed, 50 m³/fed) on growth, yield and quality of bitter gourd (Momordica charantia L.). The field experiment was laid out in a Randomized Complete Block Design with three replicates. The most important resulted obtained from this investigation can be summarized as follows : Organic fertilization of bitter melon plants with cattle manure at the rate of 50 m³/fed significantly increased growth, yield, and its components, thus the highest values of these characters were resulted from adding the highest rate of cattle manure (50 m³/fed) in both seasons. It can be recommended that organic fertilizing bitter gourd with 25 m³/fed in order to increase bitter melon yield over the control treatment and reduce the environment  pollution and production costs under the environmental conditions of Damietta Governorate, Egypt .